WEBCAST Innovative Therapies in Post-Transplant GVHD: Personal Insights from the Patient CaseBook
Graft-versus-host disease (GVHD) is a serious, life-threatening complication that can arise after allogeneic stem cell transplantation. In recent years, a better understanding of the clinical science on GVHD pathology has led to the development of multiple novel targeted strategies for treatment of acute and chronic conditions. These include agents that inhibit T-cell activation by blocking the co-stimulatory pathway for prophylaxis of acute GVHD as well as those that inhibit signaling through JAK/STAT or BTK. The management landscape of GVHD is thus poised to make a leap into an era in which multiple effective options become available for acute and chronic disease, including in patients without any current guideline-recommended or approved regimens.
PeerView’s Live CME certified, lunch symposium will utilize the “CaseBook” format, offering learners a collection of patient stories from the experts’ personal repertoire paired with analyses of how the treatment landscape in GVHD is evolving. Hematology-oncology and bone marrow transplant professionals will take a deep dive into the underlying immunology of GVHD science and the latest evidence with innovative therapeutics while also obtaining expert perspectives on the practical application of these advancements as prophylaxis or for treatment of acute and chronic,
steroid-non-responsive, and previously untreated GVHD.
THREE KEY REASONS TO ATTEND
- Gain a better understanding of key concepts in GVHD pathophysiology
- Reduce the risk of severe acute GVHD in your transplant patients
- Get the latest update on innovative therapeutics, such as JAK1/2 and BTK inhibitors, for acute and chronic GVHD
Target Audience
This activity has been designed to meet the educational needs of hematologist-oncologists, oncologists, BMT specialists, BMT nurse specialists,and other clinicians involved in the management of patients with post-transplant GVHD.
Learning Objectives
Upon completion of this activity, participants should be better able to:
• Describe the underlying immunology of post-transplant GVHD and the rationale for and mechanisms of novel therapies in the management of GVHD
• Discuss the latest evidence on novel therapies, including JAK 1/2 inhibitors, BTK inhibitors, and T-cell co-stimulation modulators, for prophylaxis or treatment of acute or chronic, steroid-naïve or steroid-refractory GVHD in the HSCT setting
• Apply the most optimal evidence-based strategies, including enrollment in clinical trials, for post-transplant GVHD care based on individual patient and disease characteristics
Support Statement
This activity is supported through educational grants from Bristol-Myers Squibb and Incyte Corporation.
Planning Director: Mary Horowitz
No one in control of content has any relevant financial relationships to disclose.
Accreditation and Credit Designation Statements
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The Medical College of Wisconsin and PVI, PeerView Institute for Medical Education.
The Medical College of Wisconsin is accredited by the ACCME to provide continuing medical education for physicians. The Medical College of Wisconsin designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only thE credit commensurate with the extent of their participation in the activity.
Available Credit
- 1.00 AMA PRA Category 1 Credit(s)™AMA PRA Category 1 Credit(s)™
- 1.00 Hours of ParticipationHours of Participation credit.

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