Through its educational arm, the ISTH Academy, the International Society on Thrombosis and Haemostasis (ISTH) has begun hosting a series of webinars on practical thrombosis and haemostasis issues that scientists and physicians frequently confront. These webinars will allot time for participants to ask questions and will cover the latest information on relevant topics.

Moderated by: Chris Ward

Inherited Platelet Disorders – Marco Cattaneo

Inherited Platelet Disorders (IPD) include Inherited Thrombocytopenias (IT) and Inherited Platelet Function Disorders (IPFD). IT are more common than generally believed and should not be confused with acquired thrombocytopenias, in order to avoid futile and potentially dangerous treatments. The bleeding manifestations of IT are very rarely severe. Some IT are associated with inherited defects in other organs or systems (syndromic IT). Inherited Platelet Function Disorders (IPFD) are also more common than generally believed. They may be associated with normal or decreased platelet cont. While clinicians should be aware of the main characteristics of IPD in order to raise the diagnostic suspicion, the definite diagnosis should be demanded to specialized laboratories, implementing complex diagnostic workups. The presentation will include a practical approach to the differential diagnosis of IT with acquired thrombocytopenias, the diagnostic workup management of IPFD. 

Genetic basis of congenital macrothrombocytopenia – Shinji Kunishima

Recent progress in the elucidation of underlying defects and the developments of diagnostic tests has renewed our understanding of congenital macrothrombocytopenia. The condition is not rare as previously thought. This presentation will address the genetic and molecular basis of congenital macrothrombocytopenia. The presentation includes a practical approach to the differential diagnosis and description of recently identified forms.