15164 - ISTH "Platelet Proteomics and Current Techniques in Measurements of Platelet Protein Phosphorylation"

Rene Zahedi - "The Use of Platelet Proteomics in Research and Diagnostics"

Khalid Naseem"Methods for Measurement of Protein Phosphorylation in Research and the Clinic"

Moderator:  Michael Tomlinson


Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of The Medical College of Wisconsin and International Society on Thrombosis and Haemostasis. The Medical College of Wisconsin is accredited by the ACCME to provide continuing medical education for physicians.
Designation of Credit Statement:
The Medical College of Wisconsin designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Please note: The course fee is $25.00 in addition to a $2.50 processing fee which is assessed for all electronic registrations.
More information and online registration:  http://www.prolibraries.com/isth/


Target Audience

The target audience should be biologists and physicians, working with both human and mouse platelets and interested in using state-of-the-art technology to further understand the role of proteins and their post-translational modifications in platelet regulation  as well as fellows and trainees interested in new methods for examining protein phosphorylation and their potential for clinical application

Learning Objectives

At the conclusion of this activity, I will be able to:

  • Explain the basics about proteomic technologies that are available as well as to study platelets and describe platelet disorders, including possibilities, limitations and pitfalls
  • Identify the limitations of the current methods used for examining protein phosphorylation in cells
  • Analyze how flow cytometry can be used for rapid examination of protein phosphorylation in whole cells
  • Outline how the use of cell permeable dyes facilitates the multiplexing of phosphorylation events in single cells leading to high throughput phosphoanalysis
  • Apply how phosphoflow can be used as a drug discovery platform
  • Demonstrate how phosphoflow can be used to allow kinetic resolution of protein phosphorylation in multiple cell type within a single whole blood sample
  • To examine how multiparameter phosphoflow can be used as a clinical tool
Additional information


Cary Clark
Phone Number: 
+1 (919) 929-3807
Course summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.00 Hours of Participation
    Hours of Participation credit.
Course opens: 
Course expires: 
Planning Committee:
Yukio Ozaki
Geoff Barnes
Chris Ward
Cary Clark
Stephen Watson
Rene Zahedi
Khalid Naseem
Michael Tomlinson
All persons in control of content have NO relevant financial relationships to disclose with the exception of the following persons:  




Chris Ward, MD


Advisory Board, Speaker


Pfizer, BMS

Advisory Board, Speaker



Advisory Board, Speaker



Advisory Board



Steering Committee Member, Speaker

Geoff Barnes

BMS, Pfizer, Blue Cross Blue Shield of Michigan

Primary Investigator & Co-Investigator

Yukio Ozaki


Advisory Board


In accordance with the ACCME®  Standards for Commercial Support Number 6, all in control of content disclosed any relevant financial relationships. These relationships were reviewed via the MCW conflict of interest resolution process and resolved



Available Credit

  • 1.00 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.00 Hours of Participation
    Hours of Participation credit.


Please login or register to take this course.

Required Hardware/software

To view the webcast on your computer go to https://www.isth.org/  click the Events/Webinars tab and view the ISTH 2015 Archived Webinars