Session date: 
Wednesday, December 10, 2014 - 12:00pm to 1:00pm
ISTH Webinar Library Once a Month
Carrboro, NC 27510
United States
  • 1.00 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.00 Hours of Participation
    Hours of Participation credit.

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Program Description: 

Through its educational arm, the ISTH Academy, the International Society on Thrombosis and Haemostasis (ISTH) has begun hosting a series of webinars on practical thrombosis and haemostasis issues that scientists and physicians frequently confront. These webinars will allot time for participants to ask questions and will cover the latest information on relevant topics.


Part ITim Warner:  Born aggregometry to high throughput 96 well plates; which test should we use?  
Presentation will briefly cover the principles and history of light transmission aggregometry leading to current user guidelines and recommendations supported by consensus agreements.  The fundamentals of 96-well plate aggregometry will be introduced and compared to those of light transmission aggregometry.  The pros and cons of using LTA and 96-well plate aggregometry in clinical and research settings will be discussed.


Part II:  Johan Heemskerk: Monitoring platelet aggregation under flow: from commercial to custom built assays
The aim of this presentation is to provide a general background of the past and present use of flow chamber devices to measure platelet aggregation and thrombus formation in whole blood. Characteristics for flow chamber tests are: that platelet adhesion and aggregation can be monitored in real time at well defined venous or arterial wall shear rates; that assays can be performed in a point-of-care setting using only small volumes of whole blood with limited handling; and that coagulation can be introduced as wished by the experimentator. Discussed will be the various types of devices and the ways of application for both experimental research questions and (pre)clinical testing of blood samples. Recent developments are widely diverging: from specialized devices where platelet aggregation is assessed in the presence of endothelial or progenitor cells; microfluidic devices that can be prepared in your own lab; to devices with microspot coatings giving a multiparameter insight into the process of thrombus formation for a certain patient.
Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of The Medical College of Wisconsin and International Society on Thrombosis and Haemostasis. The Medical College of Wisconsin is accredited by the ACCME to provide continuing medical education for physicians.
Designation of Credit Statement:
The Medical College of Wisconsin designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
More information and online registration:
Target audience: 
  • Clinicians
  • Researchers
  • Nurses
Learning objectives: 
  • To improve pathophysiological knowledge on occurrence of unwarranted clot formation 
  • To improve clinical knowledge on state-of-the-art prevention and management of venous thrombosis
Faculty & credentials: 
Planning Committee:
Yukio Ozaki
Geoff Barnes
Chris Ward
Cary Clark
Stephen Watson


  • Tim Warner, PhD, Barts & the London School of Medicine & Dentistry, United Kingdom
  • Johan Heemskerk , PhD, University of Maastricht, The Netherlands
All persons in control of content have NO relevant financial relationships to disclose with the exception of the following persons:


Commercial Interest


Yukio Ozaki


Advisory Board

Tim Warner, PhD



In accordance with the ACCME®  Standards for Commercial Support Number 6, all in control of content disclosed any relevant financial relationships. These relationships were reviewed via the MCW conflict of interest resolution process and resolved


CME Coordinator Contact Information

Cary Clark
Phone number: 
+1 (919) 929-3807