Program Description: 

Weekly grand rounds as a forum for clinical and basic research updates in neurology with respect to diagnosis and management of neurological disorders and advances in neuroscience.  General areas of focus will include among others the following:  neuromuscular, epilepsy, sleep, movement disorders, stroke and vascular disorders, neurodegenertive, dementia and memory disorders, headaches and cranial neuralgias, autonomic disorders, and general neurologic conditions.

ACCME Accreditation Statement
The Medical College of Wisconsin is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
AMA Designation of Credit Statement
The Medical College of Wisconsin designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Hours of Participation for Allied Health Professionals
The Medical College of Wisconsin designates this activity for up to 1.0 hours of participation for continuing education for allied health professionals.

Psychology CE Credit Statement:
The Medical College of Wisconsin is approved by the American Psychological Association to sponsor continuing education for psychologists.  The Medical College of Wisconsin maintains responsibility for this program and its content.
This activity contains content or processes that may be potentially stressful.

Target audience: 

Allied Health Care Professionals

Learning objectives: 

NIRS cerebral oximetry works as a noninvasive measurement that allows continuous measurement of cerebral oxygen availability. This monitor serves as a surrogate to invasive measures of venous pO2, often obtained from the jugular vein to estimate cerebral oxygen levels.

Preliminary data shows varied regional cerebral oxygen saturation and/or cytochrome oxidase redox state during interictal period and seizure activity depending on the seizure type.

The increased blood flow clearly coincided with epileptiform activity and continued to increase as the epileptiform activity built up.

Regional cerebral oxygen saturation increased in the epileptogenic focus, perhaps due to loss of cerebrovascular autoregulation.

The gap in existing technology is to simultaneously monitor cellular cytochrome c oxygenation, as a measure of mitochondrial function and oximetry for blood oxygenation. In order to move forward with an understanding of neuronal mitochondrial energy metabolism during seizures, we have developed a NIRS probe capable of measuring both regional cellular REDOX state of cytochrome c oxidase (CCO) in the neurons, and simultaneously measuring oxyhemoglobin-based regional cerebral oxygen saturation in real time.


Faculty & credentials: 

Presenter: Harry Whelan, MD

Activity Director: Derrick Shumate, DO

Planning Committee:
Ann Helms, MD
Chad Carlson, MD
David Sabsevitz, PhD


All persons in control of content have NO relevant financial relationships to disclose.


Gail Balistreri
Phone number: 
+1 (414) 955-0605
Session date: 
Friday, February 9, 2018 - 8:00am to 9:00am
Froedtert Hospital
9200 W Wisconsin Avenue
Dean Roe Auditorium
Milwaukee, WI 53226
United States
  • 1.00 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.00 APA
    APA credit.
  • 1.00 Hours of Participation
    Hours of Participation credit.

Please login or register to take this course.