Session 4: Epigenomics

In this course, students will discuss epigenetic events, the tools for the design and execution of research in this discipline, how to generate and analyze epigenomic data, and the application of Epigenomics to diagnostics, prognostics, and treatments.

Target Audience

  • Physicians
  • Nurse Practitioners
  • Physician Assistants
  • Pharmacists
  • Genetic Counselors
  • Other clinicians

Learning Objectives

Participants who engage in this education intervention will be able to:

  • Evaluate the basic principles of epigenomics and their role in precision medicine.
  • Identify potential clinical applications of epigenomics in precision medicine.
  • Formulate a framework for designing epigenomic studies in precision medicine.

 

Additional information
AttachmentSize
PDF icon PM_CME_Epigenomics in PM_Lomberk_slides.pdf7.44 MB
PDF icon PM_CME_Epigenomics in PM_Lomberk_slides.pdf7.44 MB

Contact

Name: 
Kellie LeGrave
Phone Number: 
+1 (414) 955-4139
Email: 
klegrave@mcw.edu
Course summary
Available credit: 
  • 1.50 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.50 Genetic Counselor CEU
  • 1.50 Hours of Participation
    Hours of Participation credit.
Course opens: 
03/14/2024
Course expires: 
07/12/2024
Cost:
$0.00
Part of: 
Precision Medicine Continuing Education Program Spring 2024
This module is presented with a pre-recorded PowerPoint presentation and sound.  An audio lecture is given using visual key points listed on the PowerPoint presentation.  Following the presentation, learners will be asked quiz questions to test retainment of knowledge gained in the presentation. Learners are able to complete the module at their own pace.
 

Read: Clinical epigenetics: seizing opportunities for translation | Nature Reviews Genetics

Readings: 

Epigenomic technologies for precision oncology 
Semin Cancer Biol. 2022 Sep; 84:60-68. doi: 10.1016/j.semcancer.2020.08.004 

 

Drugging the epigenome in the age of precision medicine 
Clin Epigenetics. 2023; 15: 6. PMC9832256; doi: 10.1186/s13148-022-01419-z  

 

Molecular basis of epigenetic regulation in cancer diagnosis and treatment 
Front Genet. 2022; 13: 885635. PMC9449878; doi: 10.3389/fgene.2022.885635  

 

Clinical epigenetics: seizing opportunities for translation 
Nat Rev Genet. 2019 Feb;20(2):109-127.  doi: 10.1038/s41576-018-0074-2. 
Gwen Lomberk is an Associate Professor in the Department of Surgery and the Department of Pharmacology and Toxicology at MCW. She also serves as the Chief of the Division of Research and Director of Basic Science Research for the Department of Surgery. Prior, she spent 10 years at the Mayo Clinic as Assistant and then Associate Professor of Medicine in the Division of Gastroenterology and Hepatology. Her research career has been focused on epigenomic mechanisms of disease pathobiology and the use of epigenomic-based pharmacology to serve as a robust tool for improving the future treatment of cancer.
 
Activity Director
John Meurer, MD, MBA
 

 

Planning Committee:
John Meurer, MD, MBA
Institute Director, Professor
Administration, Institute for Health & Equity

 

Bradley Stockard, PharmD
Assistant Professor
Administration, School of Pharmacy Administration

 

Jennifer Geurts, MS, CGC
Director, Assistant Professor
Administration, Institute for Health and Equity

 

In accordance with the ACCME® Standards for Integrity and Independence in Accredited Continuing Education, Standard 3, all in control of content must disclose any relevant financial relationships. The following in control of content had no relevant financial relationships to disclose.

 

  • Bradley Stockard
  • Donald Basel
  • Gwen Lomberk
  • Jake Luo
  • Jennifer Geurts
  • Jeremy Garrett
  • John Meurer
  • Michael Zimmerman

The following persons in control of content disclosed the following financial relationships which were reviewed via the MCW conflict of interest mitigation process and addressed.

 

Name

Company

Role

Honey Reddi, PhD

Belay Diagnostics

Biofidelity, Inc.

Employee

Consultant

Ben George, MD

Ipsen, Foundation Medicine,

Taiho Oncology

Consultant

 

Available Credit

  • 1.50 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.50 Genetic Counselor CEU
  • 1.50 Hours of Participation
    Hours of Participation credit.

Price

Cost:
$0.00
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