Program Description: 

Bernhard Nieswandt

“The role of platelets in acute stroke“

Stroke is the second leading cause of death worldwide with limited treatment options. Rapid restoration of blood flow by thrombolysis or thrombectomy is the mainstay of acute stroke treatment, but recanalisation of cerebral vessels may trigger ischemia/reperfusion injury and thus infarct growth “despite reperfusion”. Increasing experimental evidence now suggests that this cerebral I/R injury is a complex pathology since it involves concerted detrimental actions of platelets and T-cells, referred to as “thrombo-inflammation” which will be discussed in this webinar.

 

Martine Jandrot-Perrus

"GPVI as a novel target in thrombosis"

Dr Jandrot-Perrus will review the characteristics of platelet Glycoprotein VI (GPVI) and why GPVI is currently considered to meet the challenge of developing a safe and effective antiplatelet drug.

 

Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of The Medical College of Wisconsin and International Society on Thrombosis and Haemostasis. The Medical College of Wisconsin is accredited by the ACCME to provide continuing medical education for physicians.
 
Designation of Credit Statement:
The Medical College of Wisconsin designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
Please note: The course fee is $10.00 in addition to a $2.50 processing fee which is assessed for all electronic registrations.
 
More information and online registration:  http://academy.isth.org/isth/ 
 
 

 
Target audience: 
  • Basic and clinical scientists in the fields of thrombosis and haemostasis, inflammation, stroke and animal models of disease
  • Students, researchers and clinicians interested in translational research
Learning objectives: 

At the conclusion of this activity, I will be able to:

  • Detailed understanding of the tMCAO stroke model and the concept of “thrombo-inflammation” as the major pathomechanism underlying cerebral infarct growth in the setting of acute “experimental” stroke
  • Update knowledge on a specific platelet activation pathway differentially involved in thrombosis and physiological haemostasis
Faculty & credentials: 
Planning Committee:
Geoffrey Barnes, MD
Chris Ward, PhD
Stephen Watson, PhD

 

Bernhard Nieswandt

“The role of platelets in acute stroke“

Stroke is the second leading cause of death worldwide with limited treatment options. Rapid restoration of blood flow by thrombolysis or thrombectomy is the mainstay of acute stroke treatment, but recanalisation of cerebral vessels may trigger ischemia/reperfusion injury and thus infarct growth “despite reperfusion”. Increasing experimental evidence now suggests that this cerebral I/R injury is a complex pathology since it involves concerted detrimental actions of platelets and T-cells, referred to as “thrombo-inflammation” which will be discussed in this webinar.

 

Martine Jandrot-Perrus

"GPVI as a novel target in thrombosis"

Dr Jandrot-Perrus will review the characteristics of platelet Glycoprotein VI (GPVI) and why GPVI is currently considered to meet the challenge of developing a safe and effective antiplatelet drug.

All persons in control of content have NO relevant financial relationships to disclose with the exception of the following persons:  
 

Name

Company

Role

Geoffrey Barnes, MDPortolaConsulting
 Blue Cross Blue Shield of MichiganResearch
 BMS/PfizerResearch
Chris Ward, PhDBayerSpeaker
 Boehringer-IngelheimSpeaker, Advisory Board
 BMS/PfizerSpeaker, Advisory Board
Martine Jandrot-Perrus Acticor BiotechAdvisory Scientist

In accordance with the ACCME®  Standards for Commercial Support Number 6, all in control of content disclosed any relevant financial relationships. These relationships were reviewed via the MCW conflict of interest resolution process and resolved.

Contact

Name: 
Lacey Schmeidler, MA
Phone number: 
+1 (919) 929-3807
Email: 
lacey_schmeidler@isth.org
  • 1.00 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.00 Hours of Participation
    Hours of Participation credit.

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