Program Description: 

Mark Crowther, Peter Verhamme and Jerrold Levy recently participated in the development of an ISTH Guidance document on the reversal of DOACS. Bringing their research to an ISTH Academy webinar, they will give an overview of the results. Verhamme will discuss "Idarucizumab" and Crowther will discuss "Andexanet". Levy will moderate the session and the Q&A at the end of the presentation.

Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of The Medical College of Wisconsin and International Society on Thrombosis and Haemostasis. The Medical College of Wisconsin is accredited by the ACCME to provide continuing medical education for physicians.
Designation of Credit Statement:
The Medical College of Wisconsin designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Please note: The course fee is $10.00 in addition to a $2.50 processing fee which is assessed for all electronic registrations.
More information and online registration: 
This course is being supported by Boehringer Ingelheim & Portola Pharmaceuticals
Target audience: 

Physicians, trainees, fellows and health care professionals managing patients being treated with DOACs.

Learning objectives: 

At the conclusion of this activity, I will be able to:

  • Understand current practices for reversing Xa inhibitors
  • Manage emergencies (serious bleeding, urgent surgery) while on dabigatran
  • Understand the mode of action of idarucizucmab, the specific reversal agent of dabigatran
Faculty & credentials: 
Planning Committee:
Geoffrey Barnes, MD
Chris Ward, PhD
Stephen Watson, PhD
Yukio Ozaki

Peter Verhamme "Idarucizumab"

Mark Crowther "Andexanet"


Jerrold Levy

All persons in control of content have NO relevant financial relationships to disclose with the exception of the following persons:  




Geoffrey Barnes, MDPortolaConsulting
 Blue Cross Blue Shield of MichiganResearch
Chris Ward, PhDBayerSpeaker
 Boehringer-IngelheimSpeaker, Advisory Board
 BMS/PfizerSpeaker, Advisory Board
Jerrold Levy, MDBI, CSL Behring, JanssenSteering Committee
Peter VerhammeBoehringer, Portola, BayerInvestigator, Advisory Board, Speaker
Yukio OzakiThe Sysmex CorporationAdvisory Board
Mark CrowtherSee Attachment/sites/

In accordance with the ACCME®  Standards for Commercial Support Number 6, all in control of content disclosed any relevant financial relationships. These relationships were reviewed via the MCW conflict of interest resolution process and resolved.


Lacey Schmeidler, MA
Phone number: 
+1 (919) 929-3807
  • 1.00 AMA PRA Category 1 Credit(s)™
    AMA PRA Category 1 Credit(s)™
  • 1.00 Hours of Participation
    Hours of Participation credit.

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