In the era of “big data” and large observational trials, headline news are replete with findings linking a host of exposures from Aspirin to Zumba to various disease states.  This workshop provides a scientific framework and tools for clinicians to evaluate the associations reported in observational studies.  Participants will learn a systematic approach for critically appraising cohort studies by making reasoned inferences about observed findings in a selection of recent controversial papers.  This interactive hands-on group learning experience is designed to extend the knowledge and skills of educators and clinicians in medical schools, residency programs, or clinical practice who wish to improve their skills as practitioners and teachers of evidence-based care.  Participants should bring a laptop computer with Wi-Fi capability and a calculator for doing very simple math.
 

Thursday Characteristics of randomized and nonrandomized trials; Sources of bias in observational studies; The GRADE system; Stating the results of observational studies with accuracy; GRADE system to rate the quality of evidence

Friday Critical appraisal of cohort studies; Causation from observations of association; Spotting bias; Detecting chance findings; Probability of a true cause-and-effect relationship; EBM teaching resources